{"id":27773,"date":"2025-04-04T12:00:42","date_gmt":"2025-04-04T17:00:42","guid":{"rendered":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/?p=27773"},"modified":"2025-04-18T11:26:40","modified_gmt":"2025-04-18T16:26:40","slug":"protect-patient-health-with-salivary-diagnostics","status":"publish","type":"post","link":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/2025\/04\/04\/protect-patient-health-with-salivary-diagnostics\/","title":{"rendered":"Protect Patient Health with Salivary Diagnostics"},"content":{"rendered":"<p><a href=\"https:\/\/periolinks.com\/\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-27774 alignnone\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/04\/Kathryn-Gilliams-PerioLinks-Logo.jpg\" alt=\"\" width=\"638\" height=\"118\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/04\/Kathryn-Gilliams-PerioLinks-Logo.jpg 600w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/04\/Kathryn-Gilliams-PerioLinks-Logo-300x56.jpg 300w\" sizes=\"(max-width: 638px) 100vw, 638px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Persistent oral human papillomavirus (HPV) infections have been linked to an increased risk of oral and oropharyngeal cancer. According to the Center for Disease Control and Prevention (CDC), HPV is the most common sexually transmitted infection. Over 200 strains of HPV have been identified. The high-risk types, HPV-16 and HPV-18 are associated with oropharyngeal squamous cell carcinoma (OPSCC). The CDC reports that HPV is responsible for approximately 70% of oropharyngeal cancer in the United States.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Approximately 90% of oral HPV infections clear on their own within two years. Those that persist are linked to an increased risk of oral and oropharyngeal cancer. As a dental hygienist, I feel deeply that one of my most important responsibilities is the early detection of head and neck cancer. HPV infections are generally asymptomatic which makes early detection challenging. In addition, this is complicated by the fact that in dentistry, we don\u2019t have the technology or expertise to fully visualize the oropharynx where approximately 70% of HPV-positive cancers are located. To overcome this impediment, we can monitor our patient\u2019s HPV status with salivary diagnostic testing.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many of my coaching clients have shared that they feel uncomfortable discussing a sexually transmitted disease with their patients, as if that\u2019s outside of our scope of practice, which it is not. It is, however, outside of our comfort zone. Discussing sexually transmitted diseases was never taught when I was in dental hygiene school. Forty years ago, when I was in school, I never imagined having those conversations myself. Yet, I have learned to get over my own discomfort and have those straightforward conversations with my patients. I encourage my clients to step out of their comfort zones and share this important information with their patients, too. When we speak forthrightly and with confidence, we can help relieve our patient\u2019s discomfort, as well.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While I\u2019m performing my extra-oral and intraoral head and neck cancer screening, I typically share the following facts with patients to open the conversation:<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><span style=\"font-weight: 400;\">The risks for oral and throat cancer have changed. It used to be that people who used tobacco or excessive alcohol were at highest risk for oral or oropharyngeal cancers. Now, the biggest risk is the Human Papillomavirus. (<\/span><span style=\"font-weight: 400;\">1)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0<\/span><span style=\"font-weight: 400;\">HPV infections have historically been associated with cervical cancer, but these same strains have been found to cause oropharyngeal cancer. (<\/span><span style=\"font-weight: 400;\">1)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0<\/span><span style=\"font-weight: 400;\">HPV is easily transmitted by skin-to-skin contact, and even with open-mouth kissing. (<\/span><span style=\"font-weight: 400;\">2)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0<\/span><span style=\"font-weight: 400;\">Just as women have an annual pap smear which includes screening for genital HPV, we recommend that all adults have a screening for oral HPV. (<\/span><span style=\"font-weight: 400;\">3)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0<\/span><span style=\"font-weight: 400;\">If there is a positive result, we must repeat the test to determine if the infection resolves or if it persists. If the immune system takes longer than 2 years to clear the infection, it is considered persistent. This indicates an increased risk for oropharyngeal cancer.<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0<\/span><span style=\"font-weight: 400;\">The most effective ways to boost the immune system and have the best possible chance to clear the infection include eating whole, nutritious foods, staying well hydrated, getting good, restful sleep, daily exercise, nasal breathing and practicing stress reduction techniques. Testing for micronutrient deficiencies and supplementing with the direction of a qualified nutritionist is also recommended. (<\/span><span style=\"font-weight: 400;\">4)<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">By this point I have finished my intraoral screening with fluorescence and my extensive extra-oral screening with a very thorough neck examination. I will explain to my patient that while I have thankfully not found any sign of cancer, I can\u2019t see viruses and that is why I recommend they have an oral HPV screening with the OralDNA\u00ae Labs OraRisk\u00ae HPV test. Collecting the sample takes 30 seconds of gargling and swishing a saline solution. The sample will be sent to the lab and screened for 51 types of HPV and the results will be available in about a week. Most patients are open to the test although some need time to process the information.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">OraRisk HPV gives providers, as preventive specialists, the opportunity to offer patients an easy way to determine their HPV status and monitor positive results until the infection clears. It gives us an opportunity to refer to a throat specialist if a patient has a persistent infection to determine if any other testing or treatment is required. By utilizing this technology, dental professionals can assist in the early detection of HPV-related oropharyngeal cancer and improve patient health outcomes.<\/span><\/p>\n<p><strong>References:<\/strong><\/p>\n<ol>\n<li><span style=\"font-weight: 400;\">Elrefaey S, Massaro MA, Chiocca S, Chiesa F, Ansarin M. HPV in oropharyngeal cancer: the basics to know in clinical practice. Acta Otorhinolaryngol Ital. 2014 Oct;34(5):299-309. PMID: 25709145; PMCID: PMC4299160.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Wierzbicka M, San Giorgi MRM, Dikkers FG. Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma &#8211; A review. Rev Med Virol. 2023 Jan;33(1):e2337. doi: 10.1002\/rmv.2337. Epub 2022 Feb 22. PMID: 35194874; PMCID: PMC10078185.<\/span><\/li>\n<li><a href=\"https:\/\/my.clevelandclinic.org\/health\/diagnostics\/22163-human-papillomavirus-hpv-test\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/my.clevelandclinic.org\/health\/diagnostics\/22163-human-papillomavirus-hpv-test<\/span><\/a><\/li>\n<li><a href=\"https:\/\/www.cuimc.columbia.edu\/news\/what-you-really-need-do-boost-your-immunity\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.cuimc.columbia.edu\/news\/what-you-really-need-do-boost-your-immunity<\/span><\/a><\/li>\n<\/ol>\n<p><a href=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2024\/08\/joinoraldna.png\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-25260\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2024\/08\/joinoraldna.png\" alt=\"Join OralDNA\" width=\"1404\" height=\"401\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2024\/08\/joinoraldna.png 1404w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2024\/08\/joinoraldna-300x86.png 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2024\/08\/joinoraldna-1024x292.png 1024w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2024\/08\/joinoraldna-768x219.png 768w\" sizes=\"(max-width: 1404px) 100vw, 1404px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Persistent oral human papillomavirus (HPV) infections have been linked to an increased risk of oral and oropharyngeal cancer. According to the Center for Disease Control and Prevention (CDC), HPV is the most common sexually transmitted infection. Over 200 strains of HPV have been identified. The high-risk types, HPV-16 and HPV-18 are associated with oropharyngeal squamous <a class=\"read-more\" href=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/2025\/04\/04\/protect-patient-health-with-salivary-diagnostics\/\">Read More<\/a><\/p>\n","protected":false},"author":214,"featured_media":27774,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[167,149,58,108,110],"tags":[13,7,264,254,148,80,79,112,3,46,24,263],"class_list":["post-27773","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-oral-cancer","category-oral-hpv","category-patient-education","category-salivary-diagnostics","tag-dental-saliva-test","tag-hpv","tag-hpv-testing","tag-oral-cancer","tag-oral-cancer-awareness-month","tag-oral-hpv-and-cancer","tag-oral-hpv-test","tag-patient-education","tag-salivary-diagnostics","tag-salivary-testing","tag-testing-mouth-bacteria","tag-throat-cancer"],"jetpack_featured_media_url":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/04\/Kathryn-Gilliams-PerioLinks-Logo.jpg","jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p7W16z-7dX","_links":{"self":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/27773"}],"collection":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/users\/214"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/comments?post=27773"}],"version-history":[{"count":6,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/27773\/revisions"}],"predecessor-version":[{"id":27844,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/27773\/revisions\/27844"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/media\/27774"}],"wp:attachment":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/media?parent=27773"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/categories?post=27773"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/tags?post=27773"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}