{"id":28588,"date":"2026-01-23T12:00:16","date_gmt":"2026-01-23T18:00:16","guid":{"rendered":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/?p=28588"},"modified":"2026-01-21T12:09:01","modified_gmt":"2026-01-21T18:09:01","slug":"when-a-hopeless-tooth-isnt-hopeless","status":"publish","type":"post","link":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/2026\/01\/23\/when-a-hopeless-tooth-isnt-hopeless\/","title":{"rendered":"When a \u201cHopeless\u201d Tooth Isn\u2019t Hopeless"},"content":{"rendered":"<p><a href=\"https:\/\/leesheldonlectures.com\/\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-28601\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Lectures_Logo-Placeholder-1.jpg\" alt=\"\" width=\"544\" height=\"188\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Lectures_Logo-Placeholder-1.jpg 810w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Lectures_Logo-Placeholder-1-300x104.jpg 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Lectures_Logo-Placeholder-1-768x265.jpg 768w\" sizes=\"(max-width: 544px) 100vw, 544px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">A 45-year-old woman arrived in our office in significant pain. The day before, she had seen a dentist for a painful lower left central incisor. The recommendation was straightforward: extract the tooth and then see a periodontist.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">She refused. <\/span><span style=\"font-weight: 400;\">Instead, she searched for another option and drove nearly 50 miles to our office.<\/span><\/p>\n<h3><b>The Clinical Picture<\/b><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28591 alignnone\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Tooth-24.jpg\" alt=\"\" width=\"250\" height=\"247\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Tooth-24.jpg 558w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Tooth-24-300x296.jpg 300w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">She was hitting tooth #24 every time she closed her mouth\u2014and it hurt badly. The gingival tissue was visibly swollen, and the tooth had Class III mobility.<\/span><\/p>\n<figure id=\"attachment_28590\" aria-describedby=\"caption-attachment-28590\" style=\"width: 196px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28590\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Periapical-X-ray-of-24.jpg\" alt=\"\" width=\"196\" height=\"225\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Periapical-X-ray-of-24.jpg 422w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Periapical-X-ray-of-24-261x300.jpg 261w\" sizes=\"(max-width: 196px) 100vw, 196px\" \/><figcaption id=\"caption-attachment-28590\" class=\"wp-caption-text\">Periapical X-ray of #24<\/figcaption><\/figure>\n<figure id=\"attachment_28589\" aria-describedby=\"caption-attachment-28589\" style=\"width: 177px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28589\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/CBCT-slice-of-24.png\" alt=\"\" width=\"177\" height=\"227\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/CBCT-slice-of-24.png 368w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/CBCT-slice-of-24-234x300.png 234w\" sizes=\"(max-width: 177px) 100vw, 177px\" \/><figcaption id=\"caption-attachment-28589\" class=\"wp-caption-text\">CBCT slice of #24<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">Radiographs showed severe bone loss. At first glance, this looked like a tooth destined for extraction.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But something didn\u2019t fit.<\/span><\/p>\n<h3><b>What Didn\u2019t Add Up<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">When we probed the rest of the mouth, we found deep pockets elsewhere\u2014like a 9 mm pocket on the distal of tooth #4\u2014with surprisingly little calculus.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This wasn\u2019t typical chronic periodontitis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This was <\/span><b>aggressive periodontal disease<\/b><span style=\"font-weight: 400;\">, where the probe drops apically with almost no resistance and minimal calculus is present.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">That distinction matters.<\/span><\/p>\n<h3><b>First Visit: Stabilize, Don\u2019t Extract<\/b><\/h3>\n<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28598 alignnone\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Occlusal-adjustment.png\" alt=\"\" width=\"239\" height=\"232\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Occlusal-adjustment.png 545w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Occlusal-adjustment-300x291.png 300w\" sizes=\"(max-width: 239px) 100vw, 239px\" \/><\/span><\/p>\n<p><span style=\"font-weight: 400;\">The patient was anxious and in pain. Probing around #24 wasn\u2019t possible.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So we did three simple things:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Careful local anesthesia<\/b><span style=\"font-weight: 400;\">\u2014inject a drop of local in the vestibule. Wait for a minute. Then inject through the numb spot. Patients love it.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Occlusal adjustment<\/b>\u2014we reduced the incisal edge so she stopped traumatizing the tooth.<\/li>\n<li aria-level=\"1\"><strong>Diagnostic testing<\/strong><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">The relief was immediate once the tooth was taken out of traumatic occlusion.<\/span><\/p>\n<h3><b>Diagnostic Testing<\/b><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28633 size-large alignnone\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Blog-MPP-012326-1024x307.png\" alt=\"\" width=\"750\" height=\"225\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Blog-MPP-012326-1024x307.png 1024w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Blog-MPP-012326-300x90.png 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Blog-MPP-012326-768x230.png 768w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon-Blog-MPP-012326.png 1500w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">We collected a microbial sample and ran a MyPerioPath test from OralDNA Labs.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28596 alignleft\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Antibiotics_Sheldon-012326.png\" alt=\"\" width=\"254\" height=\"185\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Antibiotics_Sheldon-012326.png 675w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Antibiotics_Sheldon-012326-300x218.png 300w\" sizes=\"(max-width: 254px) 100vw, 254px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Testing matters because dentistry should work more like medicine: <\/span><b>identify the pathogens first, then treat.<\/b><\/p>\n<p><span style=\"font-weight: 400;\">OralDNA doesn\u2019t just identify periodontal pathogens\u2014it also helps guide <\/span><b>antibiotic selection<\/b><span style=\"font-weight: 400;\">, rather than relying on guesswork.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because this patient had a severe active infection, we started empiric antibiotics (amoxicillin and metronidazole) immediately while awaiting results.<\/span><\/p>\n<h3><b>Five Days Later<\/b><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28595 alignleft\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/5-days-later.png\" alt=\"\" width=\"209\" height=\"280\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/5-days-later.png 433w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/5-days-later-224x300.png 224w\" sizes=\"(max-width: 209px) 100vw, 209px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">The tissue had already settled down.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">My son, Dr. Matt Sheldon, splinted tooth #24 (to #23 and #25), but she was feeling better even before the splint was placed. Infection control\u2014not extraction\u2014was already changing the outcome.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h3><b>Definitive Treatment<\/b><\/h3>\n<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28594 alignleft\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/periodontal-endoscopy.png\" alt=\"\" width=\"260\" height=\"233\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/periodontal-endoscopy.png 443w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/periodontal-endoscopy-300x269.png 300w\" sizes=\"(max-width: 260px) 100vw, 260px\" \/>Next came periodontal endoscopy, allowing us to go beneath the gumline and ensure the root surfaces were truly clean.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Weeks later, pocket depths had dramatically improved\u2014nearly all were resolved.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h3><b>The Proof Is in the Bone<\/b><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28593 alignnone\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated.png\" alt=\"\" width=\"580\" height=\"342\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated.png 927w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated-300x177.png 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated-768x453.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"wp-image-28592 alignnone\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated-2.png\" alt=\"\" width=\"583\" height=\"246\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated-2.png 927w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated-2-300x127.png 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/bone-regenerated-2-768x324.png 768w\" sizes=\"(max-width: 583px) 100vw, 583px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Look at tooth #24. <\/span><span style=\"font-weight: 400;\">Bone regenerated.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This wasn\u2019t magic. It was the result of:<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><span style=\"font-weight: 400;\">Removing traumatic occlusion<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Identifying the bacterial profile<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Using appropriate antibiotics<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Thorough root debridement under direct visualization<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3><b>The Takeaway<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Patients can heal\u2014even teeth that look hopeless\u2014when we diagnose properly before we treat.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Several months later, the patient returned to the office. <\/span><span style=\"font-weight: 400;\">Not because of a problem. <\/span><span style=\"font-weight: 400;\">She came in to give me a hug. <\/span><span style=\"font-weight: 400;\">And honestly, there\u2019s no better outcome than that.<\/span><\/p>\n<h3><b>Clinical Pearl<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">When severe bone loss presents with minimal calculus, think <\/span><b>aggressive periodontal infection\u2014not mechanical failure<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Stabilize occlusion,<\/span><b> identify the pathogens<\/b><span style=\"font-weight: 400;\">, and treat the biology first. Extraction should be the last decision, not the first. <\/span><span style=\"font-weight: 400;\">To see this case in detail as well as patient resources, go to <\/span><a href=\"http:\/\/leesheldonlectures.com\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">LeeSheldonLectures.com<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.oraldna.com\/get-started\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-28177 size-large\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/08\/OralDNA_Banners-2-1024x293.png\" alt=\"\" width=\"750\" height=\"215\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/08\/OralDNA_Banners-2-1024x293.png 1024w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/08\/OralDNA_Banners-2-300x86.png 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/08\/OralDNA_Banners-2-768x219.png 768w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/08\/OralDNA_Banners-2-1536x439.png 1536w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2025\/08\/OralDNA_Banners-2-2048x585.png 2048w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A 45-year-old woman arrived in our office in significant pain. The day before, she had seen a dentist for a painful lower left central incisor. The recommendation was straightforward: extract the tooth and then see a periodontist. She refused. Instead, she searched for another option and drove nearly 50 miles to our office. The Clinical <a class=\"read-more\" href=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/2026\/01\/23\/when-a-hopeless-tooth-isnt-hopeless\/\">Read More<\/a><\/p>\n","protected":false},"author":74,"featured_media":28608,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[60,10],"tags":[9,61,78,13,125,170,147,112,76,3,245],"class_list":["post-28588","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-case-study","category-periodontal-disease","tag-bacterial-testing","tag-case-study","tag-clinical-lab-testing","tag-dental-saliva-test","tag-individualized-patient-care","tag-new-technologies","tag-oral-microbiome","tag-patient-education","tag-periodontal-disease","tag-salivary-diagnostics","tag-technology"],"jetpack_featured_media_url":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2026\/01\/Lee-Sheldon_Featured-Image.png","jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p7W16z-7r6","_links":{"self":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/28588"}],"collection":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/users\/74"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/comments?post=28588"}],"version-history":[{"count":14,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/28588\/revisions"}],"predecessor-version":[{"id":28635,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/28588\/revisions\/28635"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/media\/28608"}],"wp:attachment":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/media?parent=28588"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/categories?post=28588"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/tags?post=28588"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}