{"id":4367,"date":"2019-01-04T12:00:39","date_gmt":"2019-01-04T18:00:39","guid":{"rendered":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/?p=4367"},"modified":"2021-05-19T17:06:19","modified_gmt":"2021-05-19T22:06:19","slug":"genetic-testing-with-oraldna-labs","status":"publish","type":"post","link":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/2019\/01\/04\/genetic-testing-with-oraldna-labs\/","title":{"rendered":"Genetic Testing with OralDNA\u00ae Labs"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-4368 alignright\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Genetic-Testing-By-OralDNA-Blog-Image-300x200.jpg\" alt=\"\" width=\"450\" height=\"300\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Genetic-Testing-By-OralDNA-Blog-Image-300x200.jpg 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Genetic-Testing-By-OralDNA-Blog-Image-768x512.jpg 768w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Genetic-Testing-By-OralDNA-Blog-Image-1024x683.jpg 1024w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>Genetic testing refers to the analysis of human DNA, and has become commonplace in the practice of medicine. According to the National Institute of Health, in the future \u201cgenetic testing will be an important part of health care for many individuals\u2026we will live in a time of more effective \u2018personalized medicine\u2019. Information from genetic testing will help to detect risk for disease, guide strategies for maintaining health, offer more accurate diagnosis, and guide treatment choices for a wide variety of conditions.\u201d<sup>1\u00a0 <\/sup>\u00a0OralDNA\u00ae Labs offers several genetic tests such as Celsus One\u2122, DNA DrugMap\u2122, MyPerioID\u00ae IL-6 (included in Alert 2\u2122) and MyPerioID\u00ae IL-1. This blog will highlight general information about genetic testing along with the differences between Celsus One, Alert 2\u2122, MyPerioID\u00ae IL-6 and MyPerioID\u00ae IL-1.<\/p>\n<p>With genetic testing, our laboratory team extracts DNA from human cells within the specimen that was collected utilizing the simple 30-second swish and gargle collection technique. The gargle aids to exfoliate human cells from the cheeks, palate as well as the back of the throat. Once extraction is complete, the DNA inside the nucleus of each cell is unraveled and specific gene markers are investigated, to reveal the genotype. The genotype indicates the combination of inherited alleles received from each parent. \u00a0Genetic tests are only ordered and performed <strong>once <\/strong>in a patient\u2019s lifetime, as genetic DNA will never change.<\/p>\n<p>The genotypes, our DNA, are a blue print for how we may respond to certain stimuli such as bacteria, stress, environment etc. In the case of periodontal disease, the body <strong>usually<\/strong> responds with inflammation\/bone loss to a bacterial trigger. Two tests offered by OralDNA\u00ae Labs: MyPerioPath\u00ae and Alert 2\u2122 can identify the specific bacterial profile, but what about how the body responds? Here are some options for salivary genetic testing:<\/p>\n<p><a href=\"https:\/\/www.oraldna.com\/celsus-one-testing.html\"><strong>Celsus One\u2122<\/strong><\/a><\/p>\n<ul>\n<li>Our most<strong> comprehensive<\/strong> genetic test identifying <strong>eight gene markers: IL-6, IL-1, Beta-defensin 1, CD 14, Toll-like receptor 4, Tumor Necrosis factor alpha, IL-17A and Matrix Metallopeptidase 3<\/strong><\/li>\n<li>These gene markers have been independently researched and indicate certain genotypes will generally produce more inflammation\/bone loss<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.oraldna.com\/alert2.html\"><strong>Alert 2\u2122<\/strong><\/a> (MyPerioPath\u00ae &amp; MyPerioID\u00ae IL-6)<\/p>\n<ul>\n<li>MyPerioPath\u00ae will indicate the type and concentration of 11 disease-causing bacteria<\/li>\n<\/ul>\n<ul>\n<li>While MyPerioID\u00ae IL-6 will identify <strong>one<\/strong> gene marker within the <strong>interleukin-6<\/strong> gene, known to produce more inflammation\/bone loss<\/li>\n<li>Best Bargain<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.oraldna.com\/myPerioID.html\"><strong>MyPerioID\u00ae IL-6<\/strong><\/a><\/p>\n<ul>\n<li>Looks at <strong>one gene marker, IL-6<\/strong>, known to produce more inflammation\/bone loss<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.oraldna.com\/myPerioID.html\"><strong>MyPerioID\u00ae IL-1<\/strong><\/a><\/p>\n<ul>\n<li>Looks at <strong>one<\/strong> <strong>gene marker, IL-1<\/strong>, known to produce more inflammation\/bone loss<\/li>\n<\/ul>\n<p>The OralDNA\u00ae Labs collection supply kit and saliva collection method are universal. A single oral rinse sample collection allows you to order any and all lab tests available. MyPerioPath\u00ae, our bacterial test option that determines the type and concentration of disease-causing bacteria, can be performed multiple times on the same patient.\u00a0 Follow up MyPerioPath\u00ae testing should be performed after therapy to determine the success of bacterial reduction.<\/p>\n<p>So, you may be asking why having the genetic information is so important? Because with this information, the clinician will be able to create a more personalized risk assessment. For example, how is the patient\u2019s genetics contributing to the severity of disease? How will the patient respond to treatment? And\/or how susceptible is the patient to relapse? The clinician can now provide even further personalized patient care with this information.<\/p>\n<p>The information from these genetic test options aim to help the clinician achieve the NIH\u2019s prediction of a future where genetic information can help \u201cdetect risk for disease, guide strategies for maintaining health, offer more accurate diagnosis, and guide treatment choices for a wide variety of conditions.\u201d<sup>1<\/sup> So Test, Don\u2019t Guess!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-4369\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Table-for-Genetic-Testing-by-OralDNA-Blog-300x90.png\" alt=\"\" width=\"1000\" height=\"300\" srcset=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Table-for-Genetic-Testing-by-OralDNA-Blog-300x90.png 300w, https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Table-for-Genetic-Testing-by-OralDNA-Blog.png 700w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p>References<\/p>\n<ol>\n<li>https:\/\/report.nih.gov\/nihfactsheets\/ViewFactSheet.aspx?csid=43<br \/>\nFor more information on how to become an OralDNA Provider \u2013 scan HERE:\u00a0<a href=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2021\/05\/QR.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7542\" src=\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2021\/05\/QR.jpg\" alt=\"\" width=\"80\" height=\"80\" \/><\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>This blog will highlight general information about genetic testing along with the differences between Celsus One, Alert 2\u2122, MyPerioID\u00ae IL-6 and MyPerioID\u00ae IL-1.<\/p>\n","protected":false},"author":7,"featured_media":4368,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[11,131,10,110],"tags":[9,159,3],"class_list":["post-4367","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dental-saliva-test","category-new-technologies","category-periodontal-disease","category-salivary-diagnostics","tag-bacterial-testing","tag-genetic-testing","tag-salivary-diagnostics"],"jetpack_featured_media_url":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2019\/01\/Genetic-Testing-By-OralDNA-Blog-Image.jpg","jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p7W16z-18r","_links":{"self":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/4367"}],"collection":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/comments?post=4367"}],"version-history":[{"count":6,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/4367\/revisions"}],"predecessor-version":[{"id":7668,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/posts\/4367\/revisions\/7668"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/media\/4368"}],"wp:attachment":[{"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/media?parent=4367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/categories?post=4367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/index.php\/wp-json\/wp\/v2\/tags?post=4367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}