![\"\"](\"http:\/\/oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2017\/08\/Hygiene-is-never-routine-300x225.jpg\")
<\/p>\n<\/p>\n
The Merrian-Webster defines paradigm shift as \u201can important change that happens when the usual way of thinking about or doing something is replaced by a new and different way.\u201d There is a definite paradigm shift in dentistry and a strive to parallel our dental profession to our medical counterparts. Dr John Kempton is on this front line, helping address oral systemic health with direct patient care and as a leader inspiring others to a higher quality of care. Dr John Kempton will be our guest author for the next three weeks. Enjoy!…Richard Nagelberg, DDS.<\/em><\/p>\n Can locally focused adjunctive periodontal therapy, like hydrogen peroxide, lasers, and ozone, have any impact on the distant arterial micro-biomes? Emerging science regarding the existence of dormant-persistent pathogens and their release from all the human bacterial biomes now confronts treatment decisions. These dormant micro-biomes are now thought to be major contributors to ongoing chronic disease in the host and reinfection.[1]<\/sup><\/a>[2]<\/sup><\/a>[3]<\/sup><\/a> In fact very recently, micro-biomes were analyzed in carotid, coronary, and femoral arteries in a group of approximately 60 year old patients. These translocated colonies present with many high risk oral pathogens, with P.g. being the most abundant of all species.[4]<\/sup><\/a><\/p>\n Patients walk into our offices with on-going, concurrent systemic diseases, many have genetic susceptibility to inflammatory disease or are 50 years of age or older. These factors influence the immune response, which may place an individual at a disadvantage in fighting pathogens, locally and\/ or translocated. Our first action is to perform a salivary diagnostic test to determine the pathogens present in the oral cavity, then tailor a specific plan to address the source and the possible translocated micro-biomes.<\/p>\n The adjunctive use of specific systemic antibiotics, for high-risk patients, is currently the only therapy choice available to treat and mitigate the systemic impact of periodontitis. The standards of care need to change. In the following weeks, I will present a risk\/benefit assessment to support routine dental hygiene is never routine.<\/p>\n [1]<\/a> Potgieter M, Bester J, Kell\u00a0 DB, Pretorius E; The dormant blood micro-biome in chronic inflammatory diseases, FEMS Microbiol. Rev., 2015, 39, 567\u2013591<\/p>\n [2]<\/a> Lewis, K.;Persister cells, dormancy and infectious disease. Nature Rev. Microbiol. 2007, 5:48-56<\/p>\n [3]<\/a> Zhang, Y; Advances in the treatment of tuberculosis. Clin. Pharmacol. Ther. 82, 595\u2013600 (2007)<\/p>\n
![\"\"](\"https:\/\/www.oraldna.com\/trends-in-salivary-testing\/wp-content\/uploads\/2021\/05\/QR.jpg\")
<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"