The Link Between RA and Periodontal Disease: Bidirectional Cycle/Shared Inflammation

Posted on March 27, 2026February 19, 2026 by Dr. Jinita Parekh

The Challenge: A 29 year old female patient came in extremely concerned with her bleeding gums and wondering if that is also related to her diagnosis of rheumatoid arthritis. The Background: Age: 29 Sex: Female Medical History: Elevated Rheumatoid factor and undergoing further diagnosis to conclude diagnosis for RA Last Dental Exam: 2021 Home Care: Manual toothbrush 2x daily, floss occasionally Chief Complaint: bleeding gums, sensitive gums Clinical Assessment: ...

Perio Pathogens CAUSE Rheumatoid Arthritis– Now What?

Posted on June 9, 2017May 19, 2021 by Richard H. Nagelberg, DDS

“Rheumatoid arthritis is a chronic disease affecting over 1.3 million Americans and as much as 1% of the worldwide population.” (www.rheumatoidarthritis.org) There is a growing body of research indicating a causal association between specific periodontal pathogens and rheumatoid arthritis (RA). In a 2009 study, in Compendium of Continuing Education in Dentistry, the authors indicate that a specific perio pathogen, Porphyromonas gingivalis (P.g.), produces an enzyme capable of modifying specifi...

Periodontal Pathogens and Rheumatoid Arthritis

Posted on December 30, 2016May 12, 2021 by Richard H. Nagelberg, DDS

In December 2016 researchers from Johns Hopkins University published a study in Science Translational Medicine indicating an identified link between periodontal disease and rheumatoid arthritis (RA). It would perhaps be more accurate to indicate that rather than periodontal disease being the causative agent, the perio pathogen Aggregatibacter Actinomycetemcomitans (A.a.) was found to be involved. The link between A.a. and RA involves a process called citrullination; which is the conversion o...