Hormonal Contraceptives and the Oral Microbiome: The Missing First Signal in Salivary Diagnostics

Posted on May 15, 2026May 8, 2026 by Dr. Neusha Najafi

We’re Having the Wrong Conversation The debate around hormonal contraceptives has grown louder and more polarized. Mood changes. Inflammation. Fertility concerns. Some of these concerns are valid. Much is oversimplified. But almost all of it misses the starting point. We are debating hormones while ignoring the environment they enter. We keep focusing on hormones in isolation. Ovaries, cycles, receptors. More recently, the gut microbiome has entered the discussion through the estrobo...

Unexplained Infertility, Explained?

Posted on January 9, 2026January 8, 2026 by Dr. Neusha Najafi

Up to 30% of infertility cases remain classified as “unexplained” despite comprehensive reproductive evaluation. While this label often implies idiopathic dysfunction, it may instead reflect the limitations of current diagnostic frameworks, especially those that overlook chronic inflammation and microbial dysbiosis as contributors to reproductive failure. Emerging evidence suggests that oral health, systemic inflammation, and shared microbial exposure between partners may play a meaningfu...

Diagnostic Dialogues with Dr. Neusha Najafi DDS

Posted on August 2, 2024July 31, 2024 by Dr. Neusha Najafi

Dr. McGlennen: Tell me how you were introduced to OralDNA® salivary diagnostics. Neusha Najafi DDS: Unfortunately, I was first introduced to OralDNA at a very low point in my life. I had just suffered a late term loss at 24 weeks pregnancy called PPROM. I was told that my condition was due to an infection that caused my membrane to rupture prematurely. Up until that point, I had had zero complications in my pregnancy. The doctors said the cause of the infection was unknown and th...