The Necessity of Two Patient Specific Identifiers

All healthcare industries strive for safety and quality control, especially when handling patient information. With the OralDNA® ordering process, some may wonder why it is so important to have two matching patient specific identifiers on the OralDNA® specimen and test requisition. In this week’s blog, we will share with you the importance of patient specific identifiers and how you can accurately identify your patients’ samples. According to the College of American Pathologists (CAP) guidel...
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The Insights Provided by Salivary Testing

Without salivary testing we have no way of knowing the cause of the periodontal disease in the patients under our care. The insights provided by salivary testing include: Identification of the causative bacteria Therapeutic endpoint Risk assessment Outcomes assessment Risk of recurrence Appropriate antibiotic Incorporating the information from the salivary bacterial test into the periodontal patient’s treatment plan enables personalized care. Forget the one-size-fit...
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Periodontal Disease, Perio Pathogens & Rocket Science

Risk factors for heart attack include; age, tobacco, high blood pressure, lipid profile, diabetes, family history of heart attack, lack of physical activity, obesity, stress, illicit drug use, history of preeclampsia, history of autoimmune condition such as lupus or rheumatoid arthritis and so on and so on. Why have all these risk factors been identified? Because it is better to prevent a heart attack than it is to have one. Risk factor identification and modification is the cornerstone of p...
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Salivary Diagnostics: Your Molecular X-Ray

According to Merriam-Webster, one of the definitions of technology is a manner of accomplishing a task especially using technical processes, methods, or knowledge. This definition rings true for the introduction of clinical laboratory testing for the health care professions. It was noted in research by the NIH, “…it was not until 1896 that the first clinical laboratory was opened, a twelve-foot-by-twelve-foot room equipped at a cost of $50 at Johns Hopkins Hospital.”1 So for over a century, ...
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My Visit to OralDNA® Labs

Have you ever wondered what happens to your patient’s saliva sample once it arrives at OralDNA® Labs?  Many PDS®-supported offices have been using OralDNA® Labs to analyze the saliva of their patients, relative to the patient’s periodontal infection.  This service gives them more information about the types and severity of a patient’s infection, which is the cause of periodontitis.  Additionally, however, it tells us something about the bacterial load and a patient’s inflammatory response, w...
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OraRisk® Caries: Identifying Bacteria for Risk Assessment

Dental caries is defined as the progressive destruction of a tooth and is considered a major health issue in both adolescents and adults, in which reportedly 90% of the population is affected1.  Cavities are formed when acid erodes the hard tissues of the teeth (enamel, dentin and cementum). Acid is produced in the mouth when certain bacteria, such as Streptococcus mutans, ferment sugars into acid.  For decades, S. mutans was believed to be the main bacteria involved in caries initiation ...
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Caries Risk Assessment Duo: The Canary System® and OraRisk® Caries

In the past, controlling or treating dental caries meant restoring all areas of decay. After which, the patient was believed to be “caries controlled” until something new developed.  We now know that this thinking is flawed.  Filling or restoring caries does not treat the disease, only its effects on the tooth.  In 2001, the National Institute of Health defined caries as a disease resulting in the destruction of tooth structure by acid forming bacteria found in dental plaque in the presence ...
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“Test – and Retest – for Clinical Success”

Periodontal disease affects over half of the population and expresses itself differently in different people. It is a highly personalized disease. It is initiated by bacteria, yeast, and viruses that live in a layer on the teeth we refer to as biofilm. It is this biofilm that stimulates a unique host response. INDIVIDUAL HOST RESPONSE Each individual’s host response is dictated by combining their genetics with their acquired risk factors. Acquired risk factors are things that they can ...
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OraRisk® Caries: Identifying Bacteria for Risk Assessment

Dental caries is defined as the progressive destruction of a tooth and is considered a major health issue in both adolescents and adults, in which reportedly 90% of the population is affected(1). Cavities are formed when acid erodes the hard tissues of the teeth (enamel, dentin and cementum). Acid is produced in the mouth when certain bacteria, such as Streptococcus mutans, ferment sugars into acid. For decades, S. mutans was believed to be the main bacteria involved in caries initiation ...
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What does it mean when the report says “QNS”?

QNS is the abbreviation for Quantity Not Sufficient or Quality Not Sufficient. When referring to molecular testing, i.e. nucleic acid or DNA based tests; a final result of QNS is given when the laboratory cannot amplify the submitted sample acceptably. In the case of insufficient Quantity, this typically means that not enough human cells were collected or submitted in the sample to amplify the internal control for at least a negative test result. The internal control monitors sample colle...
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