“Test – and Retest – for Clinical Success”

Periodontal disease affects over half of the population and expresses itself differently in different people. It is a highly personalized disease. It is initiated by bacteria, yeast, and viruses that live in a layer on the teeth we refer to as biofilm. It is this biofilm that stimulates a unique host response. INDIVIDUAL HOST RESPONSE Each individual’s host response is dictated by combining their genetics with their acquired risk factors. Acquired risk factors are things that they can ...
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OraRisk® Caries: Identifying Bacteria for Risk Assessment

Dental caries is defined as the progressive destruction of a tooth and is considered a major health issue in both adolescents and adults, in which reportedly 90% of the population is affected(1). Cavities are formed when acid erodes the hard tissues of the teeth (enamel, dentin and cementum). Acid is produced in the mouth when certain bacteria, such as Streptococcus mutans, ferment sugars into acid. For decades, S. mutans was believed to be the main bacteria involved in caries initiation ...
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What does it mean when the report says “QNS”?

QNS is the abbreviation for Quantity Not Sufficient or Quality Not Sufficient. When referring to molecular testing, i.e. nucleic acid or DNA based tests; a final result of QNS is given when the laboratory cannot amplify the submitted sample acceptably. In the case of insufficient Quantity, this typically means that not enough human cells were collected or submitted in the sample to amplify the internal control for at least a negative test result. The internal control monitors sample colle...
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Patient with Chronic Gingivitis & Oral Candida

Challenge: Patient presented with chronic gingivitis and oral Candida symptoms Background: A 64-year-old female sought treatment from a medical doctor for a “thrush-like” infection. The medical doctor then referred the patient to an ENT. However, this patient was already of our record and decided to start with our office. The chief complaint is a “thrush-like” infection in the mouth, throat and lips. The clinical assessment confirmed generalized white patches. Upon periodontal assessment,...
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Interview with Dawnie Kildoo, DDS, MAGD

Dr McGlennen: Tell me how do you use OralDNA® salivary diagnostics. Dr Kildoo: We perform a MyPerioPath® on every patient with signs of periodontal disease.  It gives us a more accurate diagnosis and helps us understand possible risk factors for other systemic diseases, such as Alzheimer’s, diabetes and strokes. Recently, we have been sending the results to the patient’s physician to help them understand the oral-systemic connection, too. Dr McGlennen: What has been the physician’s rea...
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An Interview with Kristin King

      Dr McGlennen: Tell me how you use OralDNA® salivary diagnostics. Kristin RDH: We recommend OralDNA® saliva testing on all patients that have bleeding/inflammation regardless of probe depths. We utilize MyPerioPath® for these patients to customize treatment plans and target the cause of the inflammation. We utilize a post MyPerioPath®, called MyPerioProgress®, to measure the effectiveness of the therapy we provided. It is awesome to use an approach where we can ...
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Testing and Coding Improving Patient’s Health

  Periodontal disease starts with a biofilm-based infection that creates a wound that in turn, induces the inflammatory cascade responsible for the disease. This wound should be taken seriously! A variety of tests are available to determine risk, genetics, and the specific pathogens involved with periodontal disease. OralDNA® Labs salivary diagnostic testing helps improve oral health outcomes and enables patients to make more informed choices regarding their professional treatment...
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Definition: Collecting a Salivary Diagnostic Specimen

According to an article written in the Journal of Clinical Microbiology, January 2009, “Saliva is a representative diagnostic specimen for an overall view of the oral microbiota, since bacteria from various sites and surfaces of the oral cavity are found in saliva and mouth rinses.”1 The OralDNA® salivary diagnostic collection is based on this principle, among several others, supporting saliva as a testing medium. Over the past decades, cumulative research has been instrumental in elevating ...
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Flu Season… Why Is This Any Different Than An Infection In The Mouth?

Is your home plagued with the flu virus? It seems to be everywhere. The young and the elderly are those most commonly affected by it; in fact there have been many reports of death associated with the 2018 flu virus. Here’s the scenario: You bring your sick loved one to the doctor, and the doctor orders laboratory test(s) typically, by a blood and urine sample. From those lab results, a determination is made if your loved one has a virus or bacterial infection. With this valuable information ...
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Definition: CLIA certified? CAP accredited? What does this mean?

In simple terms, being CLIA certified and CAP accredited ensures your test results are meeting and exceeding industry standards for clinical laboratory testing. The Clinical Laboratory Improvement Amendments of 1988 (CLIA) are federal regulations for United States based clinical laboratories to provide industry standards for testing of human samples for diagnostic purposes. These amendments were added to the laboratory requirements outlined in the Code of Federal Regulations, 42 CFR 493. ...
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